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(11)

EP 2 809 675 A1

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(43) Date of publication: 10.12.2014 Bulletin 2014/50 (21) Application number: 12889107.4 (22) Date of filing: 30.11.2012

(51) International Patent Classification (IPC):  C07D 498/18(2006.01) A61P 35/00(2006.01) A61K 31/436(2006.01) A61P 37/00(2006.01) (86) International application number: PCT/CN2012/085631 (87) International publication number: WO 2014/082286 (05.06.2014 Gazette 2014/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (71) Applicant: Hangzhou Zylox Pharma Co., Ltd. Hangzhou, Zhejiang 310018 (CN)	(72) Inventors: WANG, Bing Hangzhou Zhejiang 310018 (CN) ZHAO, Jonathon Zhong Belle Mead New Jersey 08502 (US) (74) Representative: Prinz & Partner mbB  Patentanwälte Rundfunkplatz 2 80335 München 80335 München (DE)