(19)
(11) EP 2 811 031 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
26.12.2018 Bulletin 2018/52

(45) Mention of the grant of the patent:
11.07.2018 Bulletin 2018/28

(21) Application number: 12821102.6

(22) Date of filing: 27.12.2012
(51) International Patent Classification (IPC): 
C12Q 1/04(2006.01)
C12Q 1/37(2006.01)
C12Q 1/26(2006.01)
(86) International application number:
PCT/CU2012/000009
(87) International publication number:
WO 2013/113296 (08.08.2013 Gazette 2013/32)

(54)

COMPOSITION FROM LOBSTER HEMOCYTE EXTRACT FOR DETECTION OF LIPOPOLYSACCHARIDES, PEPTIDOGLYCANS AND 1,3-BETA-D-GLUCANS

ZUSAMMENSETZUNG AUS HUMMER-HÖMOZYTEN EXTRAKT ZUR BESTIMMUNG VON LIPOPOLYSACCHARIDEN, PEPTIDOGLYCANEN UND 1,3-BETA-D-GLUCANEN

COMPOSITION À BASE D'EXTRAIT D'HÉMOCITES DE LANGOUSTE POUR LA DÉTECTION DE LIPOPOLYSACCHARIDES, PEPTIDOGLICANES ET 1,3-ß-D-GLUCANES


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 27.12.2011 CU 20110243

(43) Date of publication of application:
10.12.2014 Bulletin 2014/50

(73) Proprietors:
  • Centro de Investigación y Desarrollo de Medicamentos (CIDEM)
    La Habana 10400 (CU)
  • Universidad de La Habana
    La Habana 10400 (CU)

(72) Inventors:
  • PERDOMO MORALES, Rolando
    La Habana 10700 (CU)
  • MONTERO ALEJO, Vivian
    La Habana 10700 (CU)
  • PERERA BRAVET, Erick
    La Habana 10700 (CU)
  • CALERO CARBONELL, Jorge Ernesto
    La Habana 10600 (CU)
  • PARDO RUIZ, Zenia
    La Habana 11500 (CU)
  • PORTO VERDECIA, Marlene
    La Habana 11300 (CU)
  • VEGA HURTADO, Yamile
    La Habana 10600 (CU)

(74) Representative: Capitán García, Maria Nuria 
ARS Privilegium, S.L. Felipe IV no. 10, bajo iz.
28014 Madrid
28014 Madrid (ES)


(56) References cited: : 
US-A- 4 970 152
US-A1- 2002 197 662
US-A- 5 310 657
US-B2- 7 598 054
   
  • PERDOMO-MORALES ET AL: "Phenoloxidase activity in the hemolymph of the spiny lobster Panulirus argus", FISH AND SHELLFISH IMMUNOLOGY, ACADEMIC PRESS, LONDON, GB, vol. 23, no. 6, 5 November 2007 (2007-11-05), pages 1187-1195, XP022328399, ISSN: 1050-4648, DOI: 10.1016/J.FSI.2007.04.001
  • JORGE HERNÁNDEZ-LÓPEZ ET AL: "In the spiny lobster (Panulirus interruptus) the prophenoloxidase is located in plasma not in haemocytes", FISH & SHELLFISH IMMUNOLOGY, vol. 14, no. 2, 1 February 2003 (2003-02-01), pages 105-114, XP055060092, ISSN: 1050-4648, DOI: 10.1006/fsim.2002.0419
  • SODERHALL K ET AL: "Role of the prophenoloxidase-activating system in invertebrate immunity", CURRENT OPINION IN IMMUNOLOGY, ELSEVIER, OXFORD, GB, vol. 10, no. 1, 1 February 1998 (1998-02-01), pages 23-28, XP004313615, ISSN: 0952-7915, DOI: 10.1016/S0952-7915(98)80026-5
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).