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EP 2 814 510 A1

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(43) Date of publication: 24.12.2014 Bulletin 2014/52 (21) Application number: 13708952.0 (22) Date of filing: 15.02.2013

(51) International Patent Classification (IPC):  A61K 45/06(2006.01) A61K 31/381(2006.01) A61K 31/4025(2006.01) A61K 31/41(2006.01) A61K 9/14(2006.01) A61K 31/4015(2006.01) A61K 31/45(2006.01) A61P 17/02(2006.01) (86) International application number: PCT/US2013/026248 (87) International publication number: WO 2013/123272 (22.08.2013 Gazette 2013/34)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 16.02.2012 US 201213398667 (71) Applicant: ALLERGAN, INC. Irvine, CA 92612 (US)

(72) Inventors: VAN EPPS, Dennis E. Goleta, CA 93117 (US) JIANG, Guang-Liang Irivne, California 92620 (US) COLLETTE, Adam L. Westminster, Massachusetts 01473 (US) HORAN, Rebecca L. Arlington, Massachusetts 02474 (US) CHEN, Jing Song Virginia Beach, Virginia 23454 (US) ALTMAN, Gregory H. Arlington, Massachusetts 02474 (US) IM, Wha-Bin Irvine, California 92612 (US) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)