(19)

(11)

EP 2 814 529 A1

(12)

(43) Date of publication: 24.12.2014 Bulletin 2014/52 (21) Application number: 13749912.5 (22) Date of filing: 13.02.2013

(51) International Patent Classification (IPC):  A61L 27/56(2006.01) A61L 27/60(2006.01) A61L 27/38(2006.01) A61L 27/54(2006.01) (86) International application number: PCT/US2013/025938 (87) International publication number: WO 2013/123049 (22.08.2013 Gazette 2013/34)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 14.02.2012 US 201261598683 P (71) Applicants: Board of Regents, The University of Texas System Austin, TX 78701 (US) Boland, Thomas El Paso, TX 79912 (US)	(72) Inventor: BOLAND, Thomas El Paso, TX 79912 (US) (74) Representative: Jones, Helen M.M.  Gill Jennings & Every LLP The Broadgate Tower 20 Primrose Street London EC2A 2ES London EC2A 2ES (GB)