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(11)

EP 2 817 324 A1

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(43) Date of publication: 31.12.2014 Bulletin 2015/01 (21) Application number: 13751500.3 (22) Date of filing: 25.02.2013

(51) International Patent Classification (IPC):  C07K 14/00(2006.01) C12N 9/12(2006.01) A61P 29/00(2006.01) A61P 21/00(2006.01) A61K 9/10(2006.01) C12N 15/09(2006.01) A61K 38/00(2006.01) A61P 37/00(2006.01) A61K 35/00(2006.01) (86) International application number: PCT/US2013/027702 (87) International publication number: WO 2013/126919 (29.08.2013 Gazette 2013/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 23.02.2012 US 201261602264 P (71) Applicant: Encode Bio Inc. Los Angeles, CA 90048 (US)	(72) Inventors: SHIVA, Nima Los Angeles, CA 90048 (US) NOWAK, Mark Pasadena, CA 91104 (US) (74) Representative: Gassner, Birgitta et al REDL Life Science Patent Attorneys Donau-City-Straße 11 1220 Wien 1220 Wien (AT)