BACILLUS, HYALURONIC ACID ENZYME, AND USES THEREOF

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EP 2 818 543 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	07.03.2018 Bulletin 2018/10

(45)	Mention of the grant of the patent:
	10.01.2018 Bulletin 2018/02

(21)	Application number: 12869142.5

(22)	Date of filing: 29.11.2012

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International Patent Classification (IPC):

C12N 1/20^(2006.01)
C12N 15/56^(2006.01)
C07K 14/32^(2006.01)
A61K 31/728^(2006.01)
A61P 9/00^(2006.01)
C12R 1/07^(2006.01)

C12N 9/26^(2006.01)
C12P 19/28^(2006.01)
A61K 8/73^(2006.01)
A61P 17/02^(2006.01)
A61Q 17/00^(2006.01)

(86)	International application number:
	PCT/CN2012/085503

(87)	International publication number:
	WO 2013/123791 (29.08.2013 Gazette 2013/35)

(54)	BACILLUS, HYALURONIC ACID ENZYME, AND USES THEREOF BACILLUS, HYALURONSÄUREENZYM UND VERWENDUNGEN DAVON BACILLE, HYALURONIDASE ET LEURS APPLICATIONS

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

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Priority:

21.02.2012 CN 201210039111
13.04.2012 CN 201210108194

(43)	Date of publication of application:
	31.12.2014 Bulletin 2015/01

(73)	Proprietor: Bloomage Freda Biopharm Co., Ltd.
	Hi-Tech Development Zone Jinan Shandong 250101 (CN)

(72)	Inventors:
	GUO, Xueping Jinan Shandong 250101 (CN) SHI, Yanli Jinan Shandong 250101 (CN) QIAO, Liping Jinan Shandong 250101 (CN) FENG, Ning Jinan Shandong 250101 (CN) WANG, Guanfeng Jinan Shandong 250101 (CN) LI, Haina Jinan Shandong 250101 (CN) XUE, Wei Jinan Shandong 250101 (CN) WANG, Haiying Jinan Shandong 250101 (CN) LUAN,Yihong Jinan Shandong 250101 (CN) LIU, Aihua Jinan Shandong 250101 (CN)

(74)	Representative: Lavoix
	Bayerstrasse 83 80335 München 80335 München (DE)

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References cited: :

EP-A1- 1 992 645
WO-A1-2008/000260
CN-A- 1 563 108
CN-A- 101 426 925
CN-A- 102 559 559
US-A1- 2011 130 339

WO-A1-00/38647
CN-A- 1 304 317
CN-A- 101 384 724
CN-A- 101 942 037
US-A1- 2007 202 570

W. MO ET AL: "The influence of hyaluronic acid on vascular endothelial cell proliferation and the relationship with ezrin/merlin expression", ACTA BIOCHIMICA ET BIOPHYSICA SINICA, vol. 43, no. 12, 19 October 2011 (2011-10-19), pages 930-939, XP055215170, ISSN: 1672-9145, DOI: 10.1093/abbs/gmr094
DATABASE GENBANK [Online] 28 January 2012 NAKAGAWA, Y. ET AL.: 'Bacillus niacini gene for 16S rRNA, partial sequence, strain: NBRC 15566', XP003033839 Database accession no. AB680904.1
DATABASE GENBANK [Online] 11 August 2011 KESHRI, J. ET AL.: 'Uncultured Bacillus sp. clone UHAS5.77 16S ribosomal RNA gene, partial sequence', XP003033840
BAI, HUIYU ET AL.: 'Research progress of preparation and application of hyaluronic acid' GUANGDONG CHEMICAL INDUSTRY vol. 37, no. 11, 31 December 2010, pages 243 - 245, XP008174336
ZHANG, HUI ET AL.: 'Preparation method of and research advances on biological activity of low molecular weight hyaluronic acid' CHINESE PHARMACEUTICAL JOURNAL vol. 47, no. 13, 31 July 2012, pages 1022 - 1024, XP008174344

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).