(19)
(11) EP 2 820 123 A1

(12)

(43) Date of publication:
07.01.2015 Bulletin 2015/02

(21) Application number: 13754938.2

(22) Date of filing: 28.02.2013
(51) International Patent Classification (IPC): 
C12N 5/0735(2010.01)
C12N 5/02(2006.01)
 C12N 5/071(2010.01)
(86) International application number:
PCT/US2013/028341
(87) International publication number:
WO 2013/130820 (06.09.2013 Gazette 2013/36)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 29.02.2012 US 201261604884 P

(71) Applicant: The Johns Hopkins University
Baltimore, MD 21218 (US)

(72) Inventors:
  • GERECHT, Sharon
    Baltimore, MD 21212 (US)
  • KUSUMA, Sravanti
    Baltimore, MD 21210 (US)

(74) Representative: Tombling, Adrian George et al
Withers & Rogers LLP 4 More London Riverside
London SE1 2AU
London SE1 2AU (GB)

   


(54) METHOD FOR GUIDING THE DERIVATION OF ENDOTHELIAL CELLS FROM HUMAN PLURIPOTENT STEM CELLS EMPLOYING TWO-DIMENSIONAL, FEEDER-FREE DIFFERENTIATION