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(11)

EP 2 825 201 A1

(12)

(43) Date of publication: 21.01.2015 Bulletin 2015/04 (21) Application number: 13761938.3 (22) Date of filing: 15.03.2013

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61P 31/00(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2013/032043 (87) International publication number: WO 2013/138716 (19.09.2013 Gazette 2013/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 15.03.2012 US 201261611297 P 18.10.2012 US 201261715634 P (71) Applicant: Ramot at Tel-Aviv University Ltd. 6139201 Tel-Aviv (IL)	(72) Inventors: SOLOMON, Beka 4639421 Herzliya (IL) DOR-ON, Eyal 4722704 Ramat Hasharon (IL) (74) Representative: Algemeen Octrooi- en Merkenbureau B.V.  P.O. Box 645 5600 AP Eindhoven 5600 AP Eindhoven (NL)