(19)
(11) EP 2 831 272 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
21.11.2018 Bulletin 2018/47

(45) Mention of the grant of the patent:
22.08.2018 Bulletin 2018/34

(21) Application number: 13715106.4

(22) Date of filing: 27.03.2013
(51) International Patent Classification (IPC): 
C12Q 1/6883(2018.01)
C12N 15/10(2006.01)
(86) International application number:
PCT/US2013/034054
(87) International publication number:
WO 2013/148807 (03.10.2013 Gazette 2013/40)

(54)

METHOD OF IDENTIFYING A SKIN-LIGHTENING AGENT

VERFAHREN ZUR IDENTIFIZIERUNG EINER HAUTAUFHELLENDEN SUBSTANZ

PROCÉDÉ DE IDENTIFICACION D'UNE SUBSTANCE DE BLANCHIMENT DE LA PEAU


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 30.03.2012 US 201261618115 P

(43) Date of publication of application:
04.02.2015 Bulletin 2015/06

(73) Proprietor: The Procter & Gamble Company
Cincinnati, OH 45202 (US)

(72) Inventors:
  • HAKOZAKI, Tomohiro
    Cincinnati, Ohio 45202 (US)
  • ZHAO, Wenzhu
    Cincinnati, Ohio 45202 (US)
  • BINDER, Robert, Lloyd
    Cincinnati, Ohio 45202 (US)
  • XU, Jun
    Cincinnati, Ohio 45202 (US)

(74) Representative: Sauvaître, Thibault Bruno 
Procter & Gamble Service GmbH IP Department Sulzbacher Straße 40-50
65824 Schwalbach am Taunus
65824 Schwalbach am Taunus (DE)


(56) References cited: : 
WO-A1-2012/011904
US-A1- 2011 150 798
US-A1- 2011 269 852
WO-A2-2012/116081
US-A1- 2011 160 080
   
  • LAMB ET AL: "The connectivity map: using gene-expression signatures to connect small molecules, genes and disease", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, vol. 313, 29 September 2006 (2006-09-29), XP008103904, ISSN: 0036-8075, DOI: 10.1126/SCIENCE.1132939 -& "Supporting Online Material forThe Connectivity Map: Using Gene-Expression Signatures to Connect SmallMolecules, Genes, and Disease", , 29 September 2006 (2006-09-29), pages 1-7, XP008103904, Retrieved from the Internet: URL:http://www.sciencemag.org/content/supp l/2006/09/29/313.5795.1929.DC1/Lamb.SOM.pd f [retrieved on 2013-05-27] -& "Table S1", , 29 September 2006 (2006-09-29), pages 1-9, XP008103904, Retrieved from the Internet: URL:http://www.sciencemag.org/content/313/ 5795/1929/suppl/DC1 [retrieved on 2013-05-27]
  • Y. ISHIMATSU-TSUJI ET AL: "Identification of novel hair-growth inducers by means of connectivity mapping", THE FASEB JOURNAL, vol. 24, no. 5, 1 May 2010 (2010-05-01), pages 1489-1496, XP055031487, ISSN: 0892-6638, DOI: 10.1096/fj.09-145292
  • "Topical N-acetyl glucosamine and niacinamide affect pigmentation-relevant gene expression in in vitro genomics experimentation", JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, C.V. MOSBY, ST. LOUIS, MO, US, vol. 56, no. 2, 1 February 2007 (2007-02-01), page AB169, XP005937344, ISSN: 0190-9622
  • BISSETT DONALD L ET AL: "Genomic expression changes induced by topical N-acetyl glucosamine in skin equivalent cultures in vitro.", JOURNAL OF COSMETIC DERMATOLOGY DEC 2007, vol. 6, no. 4, December 2007 (2007-12), pages 232-238, XP009169916, ISSN: 1473-2165
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).