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(11)

EP 2 836 223 A1

(12)

(43) Date of publication: 18.02.2015 Bulletin 2015/08 (21) Application number: 13711111.8 (22) Date of filing: 15.03.2013

(51) International Patent Classification (IPC):  A61K 35/74(2015.01) A61P 31/04(2006.01) A61K 8/99(2006.01) A61P 17/00(2006.01) (86) International application number: PCT/GB2013/050646 (87) International publication number: WO 2013/153358 (17.10.2013 Gazette 2013/42)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 13.04.2012 GB 201206599 (71) Applicant: The University Of Manchester Manchester, Greater Manchester M13 9PL (GB)	(72) Inventors: O'NEILL, Catherine Manchester Greater Manchester M13 9PL (GB) McBAIN, Andrew Manchester Greater Manchester M13 9PL (GB) (74) Representative: Salisbury, Frances et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS London EC2V 8AS (GB)