(19)

(11)

EP 2 846 762 A2

(12)

(88) Date of publication A3: 08.01.2015 (43) Date of publication: 18.03.2015 Bulletin 2015/12 (21) Application number: 13721374.0 (22) Date of filing: 22.04.2013

(51) International Patent Classification (IPC):  A61K 8/31(2006.01) A61Q 19/00(2006.01) A61K 8/34(2006.01) (86) International application number: PCT/GB2013/051005 (87) International publication number: WO 2013/167866 (14.11.2013 Gazette 2013/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 10.05.2012 GB 201208133 (71) Applicant: Croda International PLC Goole, East Yorkshire DN14 9AA (GB)	(72) Inventors: CHAVAN, Bhaven Bradford Yorkshire BD7 2JB (GB) BARNES, Alun Goole Yorkshire DN14 0GF (GB) (74) Representative: Karfopoulos, Alexis Theo  Croda Europe Limited, IP Department, Cowick Hall, Snaith, Goole, Yorkshire DN14 9AA Goole, Yorkshire DN14 9AA (GB)