(19)
(11) EP 2 858 990 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
04.07.2018 Bulletin 2018/27

(45) Mention of the grant of the patent:
16.05.2018 Bulletin 2018/20

(21) Application number: 13731212.0

(22) Date of filing: 11.06.2013
(51) International Patent Classification (IPC): 
C07D 403/12(2006.01)
C07D 213/74(2006.01)
C07D 401/02(2006.01)
C07D 401/10(2006.01)
C07D 403/04(2006.01)
C07D 403/10(2006.01)
C07D 407/12(2006.01)
C07D 413/10(2006.01)
C07D 401/14(2006.01)
C07D 213/81(2006.01)
C07D 401/04(2006.01)
C07D 401/12(2006.01)
C07D 237/14(2006.01)
C07D 407/04(2006.01)
C07D 409/04(2006.01)
(86) International application number:
PCT/US2013/045151
(87) International publication number:
WO 2013/188381 (19.12.2013 Gazette 2013/51)

(54)

PYRIDINONE AND PYRIDAZINONE DERIVATIVES

PYRIDINON- UND PYRIDAZINONDERIVATE

DÉRIVÉS DE PYRIDINONE ET DE PYRIDAZINONE


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 12.06.2012 WO PCT/CN2012/076748
12.03.2013 US 201313796437

(43) Date of publication of application:
15.04.2015 Bulletin 2015/16

(73) Proprietor: AbbVie Inc.
North Chicago, IL 60064 (US)

(72) Inventors:
  • HUBBARD, Robert, D.
    San Diego, CA 92130 (US)
  • WANG, Le
    Vernon Hills, IL 60061 (US)
  • PARK, Chang, H.
    Wadsworth, IL 60083 (US)
  • SUN, Chaohong
    Gurnee IL 60031 (US)
  • MCDANIEL, Keith, F.
    Wauconda, IL 60084 (US)
  • PRATT, John, K.
    Kenosha, WI 53142 (US)
  • SOLTWEDEL, Todd, N.
    Volo, Illinois 60030 (US)
  • WENDT, Michael, D.
    Vernon Hills, IL 60061 (US)
  • HOLMS, James, H.
    Volo, IL 60073 (US)
  • LIU, Dachun
    Vernon Hills, IL 60061 (US)
  • SHEPPARD, George, S.
    Wilmette, IL 60091 (US)

(74) Representative: Schlich, George et al
Schlich 9 St Catherine's Road
Littlehampton, West Sussex BN17 5HS
Littlehampton, West Sussex BN17 5HS (GB)


(56) References cited: : 
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WO-A1-98/55480
WO-A1-2005/065688
WO-A1-2008/072784
WO-A1-2011/109261
WO-A1-2013/045519
WO-A2-2007/133561
JP-A- 57 095 964
US-A- 4 657 906
EP-A2- 0 096 517
WO-A1-2005/049581
WO-A1-2007/008144
WO-A1-2010/069504
WO-A1-2012/129013
WO-A2-2004/022540
WO-A2-2008/013838
JP-A- 2000 178 258
US-A- 6 063 781
   
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  • ABDEL HAKEEM MAHA ET AL: "Design and synthesis of new 6-substituted pyridazine derivatives as hypotensive agents", BULLETIN OF THE FACULTY OF PHARMACY, CAIRO UNIVERSITY, FACULTY OF PHARMACY, EGYPT, vol. 46, no. 3, 1 January 2008 (2008-01-01), pages 45-56, XP009171642, ISSN: 0575-1373
  • HEWINGS D S ET AL: "3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 54, no. 19, 13 October 2011 (2011-10-13), pages 6761-6770, XP002689396, ISSN: 0022-2623, DOI: 10.1021/JM200640V [retrieved on 2011-09-06]
   
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