(19)

(11)

EP 2 859 123 A2

(12)

(88) Date of publication A3: 03.04.2014 (43) Date of publication: 15.04.2015 Bulletin 2015/16 (21) Application number: 13804085.2 (22) Date of filing: 11.06.2013

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) (86) International application number: PCT/US2013/045276 (87) International publication number: WO 2013/188471 (19.12.2013 Gazette 2013/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 11.06.2012 US 201261658317 P 17.12.2012 US 201261738277 P 11.03.2013 US 201361776647 P 15.03.2013 US 201313835093 30.05.2013 US 201361829054 P (71) Applicant: Sequenta, Inc. South San Francisco, CA 94080 (US)

(72) Inventors: FAHAM, Malek South San Francisco, CA 94080 (US) MOORHEAD, Martin South San Francisco, CA 94080 (US) WILLIS, Thomas South San Francisco, CA 94080 (US) ZHENG, Jianbiao South San Francisco, CA 94080 (US) (74) Representative: Boult Wade Tennant  Verulam Gardens 70 Gray's Inn Road London WC1X 8BT London WC1X 8BT (GB)