(19)
(11) EP 2 864 323 A1

(12)

(43) Date of publication:
29.04.2015 Bulletin 2015/18

(21) Application number: 13728404.8

(22) Date of filing: 14.06.2013
(51) International Patent Classification (IPC): 
C07D 403/14(2006.01)
A61K 31/4184(2006.01)
A61P 31/12(2006.01)
 C07D 471/04(2006.01)
A61K 31/437(2006.01)
(86) International application number:
PCT/EP2013/062322
(87) International publication number:
WO 2013/186333 (19.12.2013 Gazette 2013/51)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 15.06.2012 EP 12172271
31.08.2012 EP 12182550

(71) Applicant: Janssen Sciences Ireland UC
Little Island, County Cork (IE)

(72) Inventors:
  • TAHRI, Abdellah
    B-1070 Anderlecht (BE)
  • JONCKERS, Tim Hugo Maria
    B-2220 Heist-op-den-Berg (BE)
  • RABOISSON, Pierre Jean-Marie Bernard
    B-1331 Rosieres (BE)
  • VENDEVILLE, Sandrine Marie Helene
    B-1150 Woluwe-Saint-Pierre (BE)
  • HU, Lili
    B-2800 Mechelen (BE)
  • DEMIN, Samuël Dominique
    B-2018 Antwerpen (BE)
  • Cooymans, Ludwig Paul
    B-2340 Beerse (BE)

(74) Representative: Verberckmoes, Filip Gerard 
Janssen Pharmaceutica N.V. J&J Patent Law Department Turnhoutseweg 30
2340 Beerse
2340 Beerse (BE)

   


(54) 1,3 -DIHYDRO- 2H-BENZIMIDAZOL- 2 -ONE DERIVATIVES SUBSTITUTED WITH HETEROCYCLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS