(19)
(11) EP 2 864 788 A1

(12)

(43) Date of publication:
29.04.2015 Bulletin 2015/18

(21) Application number: 13730890.4

(22) Date of filing: 24.06.2013
(51) International Patent Classification (IPC): 
G01N 33/574(2006.01)
A61K 35/00(2006.01)
(86) International application number:
PCT/EP2013/063094
(87) International publication number:
WO 2014/001232 (03.01.2014 Gazette 2014/01)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 26.06.2012 US 201261664612 P
06.09.2012 US 201261697667 P

(71) Applicant: F.Hoffmann-La Roche AG
4070 Basel (CH)

(72) Inventors:
  • KLAUSE, Ursula
    Indianapolis, Indiana 46256 (US)
  • MOORE, Nicola
    68128 Village-Neuf (FR)
  • PALLAUD, CĂ©line
    68220 Michelbach-le-Haut (FR)
  • SCHERER, Stefan
    60329 Frankfurt a.M. (DE)
  • WILD, Norbert
    82538 Geretsried/Gelting (DE)

(74) Representative: Brodbeck, Michel et al
F. Hoffmann-La Roche AG Patent Department Grenzacherstrasse 124
4070 Basel
4070 Basel (CH)

   


(54) BLOOD PLASMA BIOMARKERS FOR BEVACIZUMAB COMBINATION THERAPIES FOR TREATMENT OF BREAST CANCER