(19)

(11)

EP 2 872 486 A1

(12)

(43) Date of publication: 20.05.2015 Bulletin 2015/21 (21) Application number: 13750947.7 (22) Date of filing: 16.07.2013

(51) International Patent Classification (IPC):  C07D 211/60(2006.01) G01N 22/00(2006.01) A61B 5/00(2006.01) G01J 3/44(2006.01) (86) International application number: PCT/IL2013/050601 (87) International publication number: WO 2014/013485 (23.01.2014 Gazette 2014/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 16.07.2012 US 201261671825 P (71) Applicant: Yeda Research and Development Co. Ltd. 76100 Rehovot (IL)	(72) Inventors: MARGULIES, David 76100 Rehovot (IL) ROUT , Bhimsen 76100 Rehovot (IN) (74) Representative: Pearl Cohen Zedek Latzer Baratz UK LLP  The Gridiron Building One Pancras Square London N1C 4AG London N1C 4AG (GB)