(19)
(11) EP 2 875 139 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
15.04.2020 Bulletin 2020/16

(45) Mention of the grant of the patent:
27.11.2019 Bulletin 2019/48

(21) Application number: 13745705.7

(22) Date of filing: 23.07.2013
(51) International Patent Classification (IPC): 
C12P 7/14(2006.01)
C12M 1/00(2006.01)
C12M 1/26(2006.01)
 C12P 7/16(2006.01)
C12M 1/02(2006.01)
(86) International application number:
PCT/GB2013/051955
(87) International publication number:
WO 2014/016576 (30.01.2014 Gazette 2014/05)

(54)

TWO-STAGE CONTINUOUS PROCESS FOR PRODUCING A SOLVENT

ZWEISTUFIGES KONTINUIERLICHES VERFAHREN ZUR HERSTELLUNG EINES LÖSUNGSMITTELS

PROCÉDÉ EN DEUX ÉTAPES CONTINU POUR LA PRODUCTION D'UN SOLVANT

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 23.07.2012 GB 201213032

(43) Date of publication of application:
27.05.2015 Bulletin 2015/22

(73) Proprietor: Biocleave Limited
Abingdon, Oxfordshire OX14 4SD (GB)

(72) Inventors:
  • GREEN, Edward
    Marlow Buckinghamshire SL7 1RU (GB)
  • DOMINGUEZ-ESPINOSA, Rosa Maria
    Reading Berkshire RG6 7ED (GB)

(74) Representative: Dehns 
St. Bride's House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)


(56) References cited: : 
EP-A1- 1 496 108
US-A- 5 063 156
 JP-A- 2008 125 456
   
  • HANNO RICHTER ET AL: "Prolonged conversion of n-butyrate to n-butanol with Clostridium saccharoperbutylacetonicum in a two-stage continuous culture with in-situ product removal", BIOTECHNOLOGY AND BIOENGINEERING, vol. 109, no. 4, 1 April 2012 (2012-04-01) , pages 913-921, XP055081864, ISSN: 0006-3592, DOI: 10.1002/bit.24380 cited in the application
  • MUTSCHLECHNER O ET AL: "Continuous two-stage ABE-fermentation using Clostridium beijerinckii NRRL B592 operating with a growth rate in the first stage vessel close to its maximal value", JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY 2000 GB, vol. 2, no. 1, 2000, pages 101-105, XP002714088, ISSN: 1464-1801 cited in the application
  • STEPHENS G M ET AL: "STUDIES ON THE STABILITY OF SOLVENT PRODUCTION BY CLOSTRIDIUM-ACETOBUTYLICUM IN CONTINUOUS CULTURE", JOURNAL OF APPLIED BACTERIOLOGY, vol. 58, no. 6, 1985, pages 597-606, XP008165108, ISSN: 0021-8847 cited in the application
   
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