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(11)

EP 2 885 445 A1

(12)

(43) Date of publication: 24.06.2015 Bulletin 2015/26 (21) Application number: 13829596.9 (22) Date of filing: 15.08.2013

(51) International Patent Classification (IPC):  C40B 40/06(2006.01) C40B 30/04(2006.01) C07H 21/04(2006.01) C40B 40/08(2006.01) C12P 19/34(2006.01) (86) International application number: PCT/US2013/055205 (87) International publication number: WO 2014/028778 (20.02.2014 Gazette 2014/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 15.08.2012 US 201261683331 P 15.03.2013 US 201361790222 P (71) Applicant: Natera, Inc. San Carlos, CA 94070 (US)	(72) Inventors: PROSEN, Dennis Foster City California 94404 (US) BANER, Johan S-11420 Stockholm (SE) HUNKAPILLER, Nathan Belmont California 94002 (US) HILL, Matthew Menlo Park California 94025 (US) ZIMMERMANN, Bernhard San Mateo California 94401 (US) (74) Representative: Webber, Philip Michael  Dehns St Bride's House 10 Salisbury Square London EC4Y 8JD London EC4Y 8JD (GB)