(19)

(11)

EP 2 888 391 A2

(12)

(88) Date of publication A3: 17.04.2014 (43) Date of publication: 01.07.2015 Bulletin 2015/27 (21) Application number: 13830466.2 (22) Date of filing: 22.08.2013

(51) International Patent Classification (IPC):  C40B 30/04(2006.01) G01N 33/567(2006.01) C07K 16/18(2006.01) (86) International application number: PCT/US2013/056201 (87) International publication number: WO 2014/031859 (27.02.2014 Gazette 2014/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 24.08.2012 US 201261693014 P 15.03.2013 US 201361787790 P (71) Applicant: University Of Utah Research Foundation Salt Lake City, UT 84108 (US)	(72) Inventors: BILD, Andrea Salt Lake City, UT 84103 (US) BUYS, Saundra Salt Lake City, UT 84109 (US) JOHNSON, William, Evan Wakefield, MA 01180 (US) (74) Representative: Michalski Hüttermann & Partner Patentanwälte mbB  Speditionstraße 21 40221 Düsseldorf 40221 Düsseldorf (DE)