(19)
(11) EP 2 897 615 A1

(12)

(43) Date of publication:
29.07.2015 Bulletin 2015/31

(21) Application number: 13838309.6

(22) Date of filing: 18.09.2013
(51) International Patent Classification (IPC): 
A61K 31/4375(2006.01)
A61K 9/20(2006.01)
 A61K 31/435(2006.01)
(86) International application number:
PCT/US2013/060387
(87) International publication number:
WO 2014/047167 (27.03.2014 Gazette 2014/13)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 18.09.2012 US 201261702586 P

(71) Applicant: Auspex Pharmaceuticals, Inc.
La Jolla, CA 92037 (US)

(72) Inventors:
  • SOMMER, Andreas
    La Jolla, CA 92037 (US)
  • ZHANG, Chengzhi
    La Jolla, CA 92037 (US)
  • CARTER, John
    La Jolla, CA 92037 (US)
  • ARTHUR, John
    La Jolla, CA 92037 (US)
  • BRADBURY, Margaret
    La Jolla, CA 92037 (US)
  • GANT, Thomas
    La Jolla, CA 92037 (US)
  • SHAHBAZ, Manouchehr
    La Jolla, CA 92037 (US)

(74) Representative: Briscoe, Paul Brian 
Rouse IP Limited 11th Floor, Exchange Tower 1 Harbour Exchange Square
London E14 9GE
London E14 9GE (GB)

   


(54) FORMULATIONS PHARMACOKINETICS OF DEUTERATED BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2