CONJUGATE OF A FRAGMENT OF A CELLULAR WALL OF A BACTERIUM AND A MUCOPOLYSACCHARIDIC CARRIER, AND USES IN MEDICINE THEREOF

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EP 2 900 274 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	08.04.2020 Bulletin 2020/15

(45)	Mention of the grant of the patent:
	20.11.2019 Bulletin 2019/47

(21)	Application number: 13824348.0

(22)	Date of filing: 25.09.2013

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International Patent Classification (IPC):

A61K 47/61^(2017.01)
C08B 37/08^(2006.01)
A61P 37/00^(2006.01)
A61P 17/00^(2006.01)

C08B 37/00^(2006.01)
A61P 31/00^(2006.01)
A61P 15/00^(2006.01)

(86)	International application number:
	PCT/IB2013/058842

(87)	International publication number:
	WO 2014/049532 (03.04.2014 Gazette 2014/14)

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CONJUGATE OF A FRAGMENT OF A CELLULAR WALL OF A BACTERIUM AND A MUCOPOLYSACCHARIDIC CARRIER, AND USES IN MEDICINE THEREOF

KONJUGAT VON EINEM FRAGMENT DER ZELLWAND EINES BAKTERIUMS UND EINEM MUCOPOLYSACCHARIDTRÄGER, UND DESSEN VERWENDUNG IN DER MEDIZIN

CONJUGUÉ D'UN FRAGMENT DE LA PAROI CELLULAIRE D'UNE BACTÉRIE ET D'UN VECTEUR MUCOPOLYSACCHARIDIQUE, ET SES UTILISATIONS MÉDICALES

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

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Priority:

25.09.2012 IT MI20121597

(43)	Date of publication of application:
	05.08.2015 Bulletin 2015/32

(73)	Proprietor: Aileens Pharma S.r.l.
	20834 Nova Milanese (MB) (IT)

(72)	Inventors:
	LONGO, Sonia 20099 Sesto S. Giovanni (IT) BIZZINI, Bernard 11000 Carcassonne (FR) VOLPATO, Ivo deceased (IT)

(74)	Representative: Coppo, Alessandro et al
	Notarbartolo & Gervasi S.p.A. Corso di Porta Vittoria, 9 20122 Milano 20122 Milano (IT)

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References cited: :

EP-A1- 1 234 584
EP-A1- 2 201 961
WO-A1-01/68128
WO-A1-2009/149155

EP-A1- 1 243 256
EP-A2- 0 497 525
WO-A1-2009/143413

MORALES A ET AL: "838 Phase 1 study with mycobacterial cell wall extract and hyaluronic acid for the intraprostatic treatment of localised prostate cancer", EUROPEAN UROLOGY SUPPLEMENTS, vol. 3, no. 2, 838, February 2004 (2004-02), page 212, XP027535491, ISSN: 1569-9056 [retrieved on 2004-02-01]
BIZZINI B ET AL: "Potentiation by nonspecific immunostimulation of the efficacy of antibiotics in the treatment of experimental bacterial infections", BIOMEDICINE AND PHARMACOTHERAPY, vol. 43, no. 10, 1989, pages 753-761, XP023756522, ISSN: 0753-3322, DOI: 10.1016/0753-3322(89)90164-9 [retrieved on 1989-01-01] cited in the application
BIZZINI B ET AL: "Induction of various cytokines in mice and activation of the complement system in rats as a part of the mechanism of action of the Corynebacterium granulosum-derived P40 immunomodulator", FEMS MICROBIOLOGY LETTERS, vol. 105, no. 4, October 1992 (1992-10), pages 171-180, XP023716203, ISSN: 0378-1097, DOI: 10.1111/J.1574-6968.1992.TB05899.X [retrieved on 1992-10-01] cited in the application

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).