MULTIMERIC MANNOSIDES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG

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EP 2 900 678 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	18.11.2020 Bulletin 2020/47

(45)	Mention of the grant of the patent:
	02.09.2020 Bulletin 2020/36

(21)	Application number: 13745375.9

(22)	Date of filing: 24.07.2013

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International Patent Classification (IPC):

C07H 15/26^(2006.01)
C07H 19/06^(2006.01)
A61K 47/61^(2017.01)

C07H 17/00^(2006.01)
A61P 31/04^(2006.01)

(86)	International application number:
	PCT/EP2013/065668

(87)	International publication number:
	WO 2014/016361 (30.01.2014 Gazette 2014/05)

(54)	MULTIMERIC MANNOSIDES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG MULTIMERE MANNOSIDE, VERFAHREN ZU DERER HERSTELLUNG UND DERER VERWENDUNGEN ALS ARZNEIMITTEL MANNOSIDES MULTIMERES, LEUR PROCÉDÉ DE PRÉPARATION ET LEURS UTILISATIONS EN TANT QUE MÉDICAMENT

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

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Priority:

24.07.2012 EP 12305906

(43)	Date of publication of application:
	05.08.2015 Bulletin 2015/32

(73)	Proprietors:
	Centre National de la Recherche Scientifique (C.N.R.S.) 75794 Paris Cedex 16 (FR) Université de Nantes 44035 Nantes Cedex 1 (FR) Université de Picardie Jules Verne 80025 Amiens Cedex 1 (FR) Université de Lille 59800 Lille (FR) Université d'Auvergne Clermont 1 63000 Clermont-Ferrand (FR)

(72)	Inventors:
	BOUCKAERT, Julie B-85000 Kortrijk (BE) GOUIN, Sébastien F-44470 Thouare Sur Loire (FR) DENIAUD, David F-44300 Saint Herblain (FR) BILYY, Rostyslav Lviv 79035 (UA) DUMYCH, Tetiana Novovolynsk Volyn Oblast 45400 (UA) SIVIGNON, Adeline F-63360 Gerzat (FR) DARFEUILLE-MICHAUD, Arlette F-63000 La Roche-Blanche (FR)

(74)	Representative: Grosset-Fournier, Chantal Catherine
	Grosset-Fournier & Demachy 54, rue Saint-Lazare 75009 Paris 75009 Paris (FR)

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References cited: :

MEHDI ALMANT ET AL: "Clustering of Escherichia coli Type-1 Fimbrial Adhesins by Using Multimeric Heptyl [alpha]-D-Mannoside Probes with a Carbohydrate Core", CHEMISTRY - A EUROPEAN JOURNAL, vol. 17, no. 36, 19 July 2011 (2011-07-19) , pages 10029-10038, XP055040461, ISSN: 0947-6539, DOI: 10.1002/chem.201100515
SÉBASTIEN&EMSP14;G. GOUIN ET AL: "Synthetic Multimeric Heptyl Mannosides as Potent Antiadhesives of Uropathogenic Escherichia coli", CHEMMEDCHEM, vol. 4, no. 5, 11 May 2009 (2009-05-11), pages 749-755, XP055040457, ISSN: 1860-7179, DOI: 10.1002/cmdc.200900034
DAVID DENIAUD ET AL: "Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, no. 4, 1 January 2011 (2011-01-01) , page 966, XP055040478, ISSN: 1477-0520, DOI: 10.1039/c0ob00389a
YOANN M CHABRE ET AL: "Chapter 6: Design and Creativity in Synthesis of Multivalent Neoglycoconjugates", 1 January 2010 (2010-01-01), ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL. 63, AMSTERDAM : ELSEVIER, PAGE(S) 165 - 393, XP009163555, ISBN: 978-0-12-380856-1 [retrieved on 2010-04-08] page 224 - page 225
Julie Bouckaert ET AL: "-Mannosides Grafted on a [beta]-Cyclodextrin Core To Interfere with Escherichia coli Adhesion: An In Vivo Multivalent Effect", CHEMISTRY - A EUROPEAN JOURNAL, vol. 19, no. 24, 17 April 2013 (2013-04-17), pages 7847-7855, XP055231133, ISSN: 0947-6539, DOI: 10.1002/chem.201204015


	Remarks:
	The file contains technical information submitted after the application was filed and not included in this specification

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