(19)

(11)

EP 2 912 463 A1

(12)

(43) Date of publication: 02.09.2015 Bulletin 2015/36 (21) Application number: 13849032.1 (22) Date of filing: 25.10.2013

(51) International Patent Classification (IPC):  G01N 33/53(2006.01) C07K 14/435(2006.01) C12Q 1/68(2006.01) C12N 9/00(2006.01) (86) International application number: PCT/SG2013/000460 (87) International publication number: WO 2014/065760 (01.05.2014 Gazette 2014/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 25.10.2012 SG 201207942 (71) Applicant: Agency for Science, Technology and Research Singapore 138632 (SG)	(72) Inventors: GHADESSY, Farid Singapore 138648 (SG) VERMA, Chandra Shekhar Singapore 138671 (SG) LANE, David Philip Singapore 138648 (SG) SIAU, Jia Wei Singapore 138648 (SG) JOSEPH, Thomas Leonard Singapore 138671 (SG) SIM, Adelene Yen Ling Singapore 138671 (SG) (74) Representative: Durán-Corretjer, S.L.P.  Còrsega, 329 (Paseo de Gracia/Diagonal) 08037 Barcelona 08037 Barcelona (ES)