(19)

(11)

EP 2 917 185 A1

(12)

(43) Date of publication: 16.09.2015 Bulletin 2015/38 (21) Application number: 13785876.7 (22) Date of filing: 04.11.2013

(51) International Patent Classification (IPC):  C07D 239/94(2006.01) A61P 35/00(2006.01) A61K 31/47(2006.01) (86) International application number: PCT/EP2013/072914 (87) International publication number: WO 2014/072244 (15.05.2014 Gazette 2014/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 09.11.2012 EP 12191959 (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim am Rhein (DE)

(72) Inventors: BLUM, Martin 55216 Ingelheim Am Rhein (DE) GOTTSCHLING, Dirk 55216 Ingelheim Am Rhein (DE) HECKEL, Armin 55216 Ingelheim Am Rhein (DE) HEHN, Joerg 55216 Ingelheim Am Rhein (DE) LEHMANN, Thorsten 55216 Ingelheim Am Rhein (DE) WIEDENMAYER, Dieter 55216 Ingelheim Am Rhein (DE) (74) Representative: Simon, Elke Anna Maria et al Boehringer Ingelheim GmbH Binger Strasse 173 55216 Ingelheim am Rhein 55216 Ingelheim am Rhein (DE)