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EP 2 925 312 A1

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(43) Date of publication: 07.10.2015 Bulletin 2015/41 (21) Application number: 13858101.2 (22) Date of filing: 21.11.2013

(51) International Patent Classification (IPC):  A61K 31/277(2006.01) A61P 3/04(2006.01) A61P 3/06(2006.01) A61P 9/12(2006.01) A61P 13/12(2006.01) A61P 3/00(2006.01) A61P 3/10(2006.01) A61P 9/00(2006.01) A61P 9/10(2006.01) A61P 1/16(2006.01) (86) International application number: PCT/CN2013/087581 (87) International publication number: WO 2014/082544 (05.06.2014 Gazette 2014/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 28.11.2012 CN 201210497436 (71) Applicant: National Institute Of Biological Sciences, Beijing Beijing 102206 (CN)	(72) Inventors: HUANG, Niu Beijing 102206 (CN) ZHI, Gang Beijing 102206 (CN) CHAI, Jijie Beijing 102206 (CN) PENG, Shiming Beijing 102206 (CN) HOU, Nannan Beijing 102206 (CN) (74) Representative: Viering, Jentschura & Partner Patent- und Rechtsanwälte  Kennedydamm 55 / Roßstrasse 40476 Düsseldorf 40476 Düsseldorf (DE)