(19)

(11)

EP 2 948 161 A1

(12)

(43) Date of publication: 02.12.2015 Bulletin 2015/49 (21) Application number: 14706362.2 (22) Date of filing: 24.01.2014

(51) International Patent Classification (IPC):  A61K 38/16(2006.01) A61P 21/00(2006.01) A61K 38/17(2006.01) (86) International application number: PCT/US2014/012996 (87) International publication number: WO 2014/116981 (31.07.2014 Gazette 2014/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 25.01.2013 US 201361756996 P 13.12.2013 US 201361915733 P (71) Applicant: Shire Human Genetic Therapies, Inc. Lexington, MA 02421 (US)	(72) Inventor: MINEAU, Rochelle Lexington, Massachusetts 02421 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)