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(11)

EP 2 968 336 A2

(12)

(88) Date of publication A3: 04.12.2014 (43) Date of publication: 20.01.2016 Bulletin 2016/03 (21) Application number: 14710651.2 (22) Date of filing: 03.03.2014

(51) International Patent Classification (IPC):  A61K 31/519(2006.01) A61K 31/4709(2006.01) A61K 31/513(2006.01) A61K 31/5377(2006.01) A61K 31/66(2006.01) A61P 35/00(2006.01) A61K 31/404(2006.01) A61K 31/506(2006.01) A61K 31/517(2006.01) A61K 31/553(2006.01) A61K 45/06(2006.01) (86) International application number: PCT/IB2014/059401 (87) International publication number: WO 2014/140989 (18.09.2014 Gazette 2014/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 14.03.2013 US 201361786130 P (71) Applicant: Pfizer Inc. New York, NY 10017 (US)	(72) Inventors: GOLDBERG, Zelanna Iris San Diego, California 92122 (US) KATH, John Charles La Mesa. California 91941 (US) LETRENT, Stephen Paul Princeton, New Jersey 08540 (US) WEINRICH, Scott Lawrence San Diego, California 92130 (US) (74) Representative: Pfizer  European Patent Department 23-25 avenue du Docteur Lannelongue 75668 Paris Cedex 14 75668 Paris Cedex 14 (FR)