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EP 2 968 532 A1

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(43) Date of publication: 20.01.2016 Bulletin 2016/03 (21) Application number: 13785756.1 (22) Date of filing: 18.10.2013

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/24(2006.01) C07K 1/16(2006.01) C07K 1/22(2006.01) C07K 1/20(2006.01) C07K 1/36(2006.01) C07K 1/18(2006.01) C07K 1/34(2006.01) (86) International application number: PCT/US2013/065797 (87) International publication number: WO 2014/143185 (18.09.2014 Gazette 2014/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 14.03.2013 WO PCT/US2013/031352 (71) Applicant: AbbVie Inc. North Chicago, IL 60064 (US)	(72) Inventors: HERIGSTAD, Matthew Omon Charlestown, MA 02129 (US) RICH, Linda E. Worcester, MA 01605 (US) LU, Stephen, Ming-teh Worcester, MA 01606 (US) RAMASUBRAMANYAN, Natarajan Westborough, MA 01581 (US) (74) Representative: Miller, David James et al Mathys & Squire LLP The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)