(19)
(11) EP 2 968 591 A1

(12)

(43) Date of publication:
20.01.2016 Bulletin 2016/03

(21) Application number: 14723916.4

(22) Date of filing: 12.03.2014
(51) International Patent Classification (IPC): 
A61K 47/48(2006.01)
C07D 405/14(2006.01)
C07D 401/12(2006.01)
 A61P 35/00(2006.01)
C07D 233/64(2006.01)
C07D 249/10(2006.01)
(86) International application number:
PCT/US2014/024795
(87) International publication number:
WO 2014/151030 (25.09.2014 Gazette 2014/39)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 15.03.2013 US 201361799384 P
23.08.2013 US 201361869496 P

(71) Applicants:
  • Novartis AG
    4056 Basel (CH)
  • IRM LLC
    Hamilton HM LX (BM)

(72) Inventors:
  • BARSANTI, Paul A.
    Emeryville, California 94608 (US)
  • CHAMOIN, Sylvie
    4002 Basel (CH)
  • DOUMAMPOUOM-METOUL, Lionel
    4002 Basel (CH)
  • GEIERSTANGER, Bernard Hubert
    San Diego, California 92121 (US)
  • GROTZFELD, Robert Martin
    4002 Basel (CH)
  • GUERRO-LAGASSE, Stephanie
    4002 Basel (CH)
  • JONES, Darryl Brynley
    4002 Basel (CH)
  • KARPOV, Alexei
    4002 Basel (CH)
  • LAFRANCE, Marc
    4002 Basel (CH)
  • NIETO-OBERHUBER, Cristina
    4002 Basel (CH)
  • OU, Weijia
    San Diego, California 92121 (US)
  • PIIZZI, Grazia
    4002 Basel (CH)

(74) Representative: Dyer, James et al
Novartis Pharma AG Patent Department
4002 Basel
4002 Basel (CH)

   


(54) CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF