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(11)

EP 2 970 193 A1

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(43) Date of publication: 20.01.2016 Bulletin 2016/03 (21) Application number: 14718832.0 (22) Date of filing: 12.03.2014

(51) International Patent Classification (IPC):  C07D 401/12(2006.01) C07D 403/04(2006.01) C07D 405/12(2006.01) C07D 409/10(2006.01) C07D 413/10(2006.01) C07D 207/36(2006.01) A61K 31/4439(2006.01) A61K 31/4725(2006.01) C07D 401/10(2006.01) C07D 403/10(2006.01) C07D 407/12(2006.01) C07D 409/12(2006.01) C07D 471/04(2006.01) C07D 403/12(2006.01) A61K 31/4704(2006.01) (86) International application number: PCT/US2014/024508 (87) International publication number: WO 2014/165127 (09.10.2014 Gazette 2014/41)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 12.03.2013 US 201361777749 P (71) Applicant: AbbVie Inc. North Chicago, IL 60064 (US)

(72) Inventors: HASVOLD, Lisa, A. Grayslake, Illinois 60030 (US) LIU, Dachun Vernon Hills, Illinois 60061 (US) PRATT, John, K. Kenosha, Wisconsin 53142 (US) SHEPPARD, George, S. Wilmette, Illinois 60091 (US) MCDANIEL, Keith, F. Wauconda, Illinois 60084 (US) ELMORE, Steven, W. Northbrook, Illinois 60062 (US) HUBBARD, Robert, D. San Diego, California 92130 (US) (74) Representative: Modiano, Micaela Nadia  Modiano & Partners Thierschstrasse 11 80538 München 80538 München (DE)