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EP 2 970 257 A1

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(43) Date of publication: 20.01.2016 Bulletin 2016/03 (21) Application number: 14709488.2 (22) Date of filing: 21.02.2014

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) A61K 31/437(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2014/017751 (87) International publication number: WO 2014/158528 (02.10.2014 Gazette 2014/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 14.03.2013 US 201361781070 P 10.02.2014 US 201414176506 (71) Applicant: AbbVie Inc. North Chicago, IL 60064 (US)

(72) Inventors: TAO, Zhi-Fu Vernon Hills, IL 60061 (US) WANG, Xilu Libertyville, IL 60048 (US) WENDT, Michael, D. Vernon Hills, IL 60061 (US) SOUERS, Andrew, J. Libertyville, IL 60048 (US) JUDD, Andrew, S. Grayslake, IL 60030 (US) KUNZER, Aaron Arlington Heights, IL 60004 (US) SULLIVAN, Gerard Lake Villa, IL 60046 (US) (74) Representative: Modiano, Micaela Nadia et al Modiano & Partners Thierschstrasse 11 80538 München 80538 München (DE)