(19)
(11) EP 2 970 478 A1

(12)

(43) Date of publication:
20.01.2016 Bulletin 2016/03

(21) Application number: 14720298.0

(22) Date of filing: 11.03.2014
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
C07K 14/005(2006.01)
C07K 14/25(2006.01)
A61K 39/00(2006.01)
(86) International application number:
PCT/US2014/023198
(87) International publication number:
WO 2014/164680 (09.10.2014 Gazette 2014/41)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 12.03.2013 US 201361777130 P

(71) Applicant: Molecular Templates, Inc.
Georgetown, TX 78626 (US)

(72) Inventors:
  • POMA, Eric
    New York New York 10014 (US)
  • WILLERT, Erin
    Round Rock Texas 78681 (US)
  • KIM, Jason
    Austin Texas 78759 (US)
  • HIGGINS, Jack
    Georgetown Texas 78628 (US)
  • RAJAGOPALAN, Sangeetha
    Round Rock Texas 78665 (US)

(74) Representative: Griffin, Philippa Jane et al
Mathys & Squire LLP The Shard 32 London Bridge Street
London SE1 9SG
London SE1 9SG (GB)

   


(54) CD20-BINDING IMMUNOTOXINS FOR INDUCING CELLULAR INTERNALIZATION AND METHODS USING SAME