(19)

(11)

EP 2 970 833 A1

(12)

(43) Date of publication: 20.01.2016 Bulletin 2016/03 (21) Application number: 14764055.1 (22) Date of filing: 14.03.2014

(51) International Patent Classification (IPC):  C11D 3/48(2006.01) A01N 25/02(2006.01) A61K 31/14(2006.01) (86) International application number: PCT/US2014/028008 (87) International publication number: WO 2014/143857 (18.09.2014 Gazette 2014/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 15.03.2013 US 201361788426 P (71) Applicant: University of North Carolina at Chapel Hill Chapel Hill, NC 27599 (US)	(72) Inventors: ZAMBONI, William Chapel Hill, NC 27517 (US) O'NEILL, Tom Potomac, MD 20854 (US) ECKEL, Stephen Chapel Hill, NC 27514 (US) (74) Representative: Johnson, Yvonne Catherine  Barker Brettell LLP 100 Hagley Road Edgbaston Birmingham B16 8QQ Edgbaston Birmingham B16 8QQ (GB)