(19)
(11) EP 2 972 374 A2

(12)

(88) Date of publication A3:
05.03.2015

(43) Date of publication:
20.01.2016 Bulletin 2016/03

(21) Application number: 14723537.8

(22) Date of filing: 12.03.2014
(51) International Patent Classification (IPC): 
G01N 33/574(2006.01)
(86) International application number:
PCT/US2014/024936
(87) International publication number:
WO 2014/151079 (25.09.2014 Gazette 2014/39)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 15.03.2013 US 201313841176

(71) Applicant: The United States of America, as represented by The Secretary, Department of Health and Human Services
Bethesda, MD 20892-7660 (US)

(72) Inventors:
  • HEWITT, Stephen, M.
    Potomac, MD 20854 (US)
  • CHUNG, Joon-yong
    Rockville, MD 20850 (US)
  • GUHA, Udayan
    Bethesda, MD 20814 (US)

(74) Representative: Green, Katherine et al
Mewburn Ellis LLP City Tower 40 Basinghall Street
London EC2V 5DE
London EC2V 5DE (GB)

   


(54) RATIO BASED BIOMARKERS AND METHODS OF USE THEREOF