(19)
(11) EP 2 999 692 A1

(12)

(43) Date of publication:
30.03.2016 Bulletin 2016/13

(21) Application number: 14724762.1

(22) Date of filing: 19.05.2014
(51) International Patent Classification (IPC): 
C07D 223/16(2006.01)
(86) International application number:
PCT/EP2014/060221
(87) International publication number:
WO 2014/187768 (27.11.2014 Gazette 2014/48)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 20.05.2013 EP 13168419

(71) Applicant: LEK Pharmaceuticals d.d.
1526 Ljubljana (SI)

(72) Inventors:
  • STAVBER, Gaj
    1526 Ljubljana (SI)
  • CLUZEAU, Jerome
    1526 Ljubljana (SI)

(74) Representative: Prüfer & Partner mbB Patentanwälte · Rechtsanwälte 
Sohnckestraße 12
81479 München
81479 München (DE)

   


(54) NOVEL SYNTHETIC PROCESSES TO 8-CHLORO-3-BENZO[D]AZEPINE VIA FRIEDEL-CRAFTS ALKYLATION OF OLEFIN