(19)
(11) EP 3 003 487 A1

(12)

(43) Date of publication:
13.04.2016 Bulletin 2016/15

(21) Application number: 14807612.8

(22) Date of filing: 03.06.2014
(51) International Patent Classification (IPC): 
A61P 19/10(2006.01)
(86) International application number:
PCT/US2014/040704
(87) International publication number:
WO 2014/197477 (11.12.2014 Gazette 2014/50)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 05.06.2013 US 201361831542 P

(71) Applicant: Repros Therapeutics Inc.
The Woodlands, TX 77380 (US)

(72) Inventors:
  • PODOLSKI, Joseph, S.
    The Woodlands, TX 77381 (US)
  • HSU, Kuang
    The Woodlands, TX 77381 (US)
  • WIEHLE, Ronald, D.
    Houston, TX 77059 (US)
  • FONTENOT, Greg
    The Woodlands, TX 77381 (US)
  • THOMPSON, Jaye
    The Woodlands, TX 77381 (US)

(74) Representative: Nederlandsch Octrooibureau 
P.O. Box 29720
2502 LS The Hague
2502 LS The Hague (NL)

   


(54) TRANS-CLOMIPHENE AND ITS ANALOGUES AS AGENTS THAT INCREASE BONE MINERAL DENSITY