(19)
(11) EP 3 004 340 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
04.11.2020 Bulletin 2020/45

(45) Mention of the grant of the patent:
08.07.2020 Bulletin 2020/28

(21) Application number: 14763905.8

(22) Date of filing: 14.03.2014
(51) International Patent Classification (IPC): 
C12N 9/50(2006.01)
A61K 38/48(2006.01)
A61P 31/04(2006.01)
A23L 33/00(2016.01)
A61P 1/14(2006.01)
(86) International application number:
PCT/CA2014/000258
(87) International publication number:
WO 2014/138927 (18.09.2014 Gazette 2014/38)

(54)

TREATMENT OF GLUTEN INTOLERANCE AND RELATED CONDITIONS

BEHANDLUNG VON GLUTENUNVERTRÄGLICHKEIT UND VERWANDTEN LEIDEN

TRAITEMENT DE L'INTOLÉRANCE AU GLUTEN ET D'ÉTATS ASSOCIÉS


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 15.03.2013 US 201313843369

(43) Date of publication of application:
13.04.2016 Bulletin 2016/15

(60) Divisional application:
20184407.3

(73) Proprietor: Codexis, Inc.
Redwood City, CA 94063 (US)

(72) Inventors:
  • SCHRIEMER, David
    Destin, Florida 32541-2924 (US)
  • MAN, Petr
    Destin, Florida 32541-2924 (US)
  • MRAZEK, Hynek
    Destin, Florida 32541-2924 (US)
  • REY, Martial
    Destin, Florida 32541-2924 (US)

(74) Representative: Gibson, Mark 
Sagittarius IP Marlow International Parkway
Marlow SL7 1YL
Marlow SL7 1YL (GB)


(56) References cited: : 
EP-A2- 2 090 662
US-A1- 2012 225 050
   
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  • NAOYA HATANO ET AL: "Proteome Analysis of Pitcher Fluid of the Carnivorous Plant Nepenthes alata", JOURNAL OF PROTEOME RESEARCH., vol. 7, no. 2, 1 February 2008 (2008-02-01), pages 809-816, XP055313727, US ISSN: 1535-3893, DOI: 10.1021/pr700566d
  • M. REY ET AL: "Nepenthesin from Monkey Cups for Hydrogen/Deuterium Exchange Mass Spectrometry", MOLECULAR & CELLULAR PROTEOMICS, vol. 12, no. 2, 29 November 2012 (2012-11-29), pages 464-472, XP055313730, US ISSN: 1535-9476, DOI: 10.1074/mcp.M112.025221
  • AN CHUNG-IL ET AL: "Aspartic proteinases are expressed in pitchers of the carnivorous plant Nepenthes alata Blanco", PLANTA, SPRINGER VERLAG, DE, vol. 214, no. 5, 1 March 2002 (2002-03-01) , pages 661-667, XP002453529, ISSN: 0032-0935, DOI: 10.1007/S004250100665
  • MAZORRA-MANZANO MA ET AL.: 'Structure-function characterization of the recombinant aspartic proteinase A1 from Arabidopsis thaliana' PHYTOCHEM vol. 71, no. 5-6, April 2010, pages 515 - 523, XP055292809
  • STEPNIAK D ET AL.: 'Highly-efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease' AM J PHYSIOL vol. 291, pages G621 - G629, XP002741636
  • TAKAHASHI K ET AL.: 'Nepenthesin, a unique member of a novel subfamily of aspartic proteinases: Enzymatic and structural characteristics' CURR PROT PEP SCI vol. 6, 2005, pages 513 - 525, XP008181083
   
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