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(11)

EP 3 049 440 A1

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(43) Date of publication: 03.08.2016 Bulletin 2016/31 (21) Application number: 14782039.3 (22) Date of filing: 25.09.2014

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C07K 16/32(2006.01) (86) International application number: PCT/US2014/057432 (87) International publication number: WO 2015/048272 (02.04.2015 Gazette 2015/13)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 25.09.2013 US 201361882428 P (71) Applicant: Amgen Inc. Thousand Oaks, California 91320-1799 (US)	(72) Inventors: MICHAELS, Mark, L. Encino, CA 91316 (US) BORGES, Luis, G. San Mateo, CA 94044 (US) YAN, Wei Sammamish, WA 98075 (US) (74) Representative: Schiweck, Weinzierl & Koch  European Patent Attorneys Landsberger Straße 98 80339 München 80339 München (DE)