(19)
(11) EP 3 060 179 A1

(12)

(43) Date of publication:
31.08.2016 Bulletin 2016/35

(21) Application number: 14862905.8

(22) Date of filing: 22.10.2014
(51) International Patent Classification (IPC): 
A61F 6/06(2006.01)
A61K 9/00(2006.01)
A61K 31/565(2006.01)
(86) International application number:
PCT/US2014/061811
(87) International publication number:
WO 2015/073177 (21.05.2015 Gazette 2015/20)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 22.10.2013 US 201361894411 P
06.12.2013 US 201314099562
27.01.2014 US 201461932140 P

(71) Applicant: Therapeuticsmd, Inc.
Boca Raton, Florida 33487 (US)

(72) Inventors:
  • BERNICK, Brian A.
    Boca Raton, Florida 33496 (US)
  • THORSTEINSSON, Thorsteinn
    West Palm Beach, Florida 33411 (US)
  • PERSICANER, Peter H. R.
    Boca Raton, Florida 33496 (US)
  • CACACE, Janice Louise
    Miami, Florida 33137 (US)
  • AMADIO, Julia M.
    Boca Raton, Florida 33486 (US)
  • SANSCILIO, Frederick D.
    Palm Beach Gardens, Florida 33418 (US)
  • IRANI, Neda
    Palm Beach Gardens, Florida 33410 (US)

(74) Representative: Main, Malcolm Charles 
Murgitroyd & Company Scotland House 165-169 Scotland Street
Glasgow G5 8PL
Glasgow G5 8PL (GB)

   


(54) VAGINAL INSERTED ESTRADIOL PHARMACEUTICAL COMPOSITONS AND METHODS