(19)

(11)

EP 3 065 700 A1

(12)

(43) Date of publication: 14.09.2016 Bulletin 2016/37 (21) Application number: 13786678.6 (22) Date of filing: 07.11.2013

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 31/497(2006.01) A61K 47/26(2006.01) (86) International application number: PCT/EP2013/073301 (87) International publication number: WO 2015/067313 (14.05.2015 Gazette 2015/19)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (71) Applicant: Synthon B.V. 6545 CM Nijmegen (NL)	(72) Inventors: BAKKER-HOLMDAHL, Lisa NL-6545 CM Nijmegen (NL) HAAN DE, Frans Henri Nicolaas NL-6545 CM Nijmegen (NL) MURPANI, Deepak NL-6545 CM Nijmegen (NL) (74) Representative: Mendivil Gil, Maria Dolores  Synthon BV IP Research P.O. Box 7071 6503 GN Nijmegen 6503 GN Nijmegen (NL)