(19)
(11) EP 3 066 090 A1

(12)

(43) Date of publication:
14.09.2016 Bulletin 2016/37

(21) Application number: 14796082.7

(22) Date of filing: 07.11.2014
(51) International Patent Classification (IPC): 
C07D 401/04(2006.01)
C07D 403/14(2006.01)
A61K 31/404(2006.01)
 C07D 403/04(2006.01)
C07D 409/04(2006.01)
A61P 25/00(2006.01)
(86) International application number:
PCT/EP2014/074099
(87) International publication number:
WO 2015/067782 (14.05.2015 Gazette 2015/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 08.11.2013 EP 13192224
08.11.2013 US 201314076016
03.11.2014 BE 201400845

(71) Applicant: iTeos Therapeutics
6041 Charleroi (BE)

(72) Inventors:
  • CROSIGNANI, Stefano
    B-1400 Nivelles (BE)
  • CAUWENBERGHS, Sandra
    B-1500 Halle (BE)
  • DEROOSE, Frederik
    B-9070 Destelbergen (BE)
  • DRIESSENS, Gregory
    B-1170 Watermael-Boitsfort (BE)

(74) Representative: Pfizer 
European Patent Department 23-25 avenue du Docteur Lannelongue
75668 Paris Cedex 14
75668 Paris Cedex 14 (FR)

   


(54) 4-(INDOL-3-YL)-PYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE