(19)

(11)

EP 3 068 288 A2

(12)

(88) Date of publication A3: 29.10.2015 (43) Date of publication: 21.09.2016 Bulletin 2016/38 (21) Application number: 14861958.8 (22) Date of filing: 14.11.2014

(51) International Patent Classification (IPC):  A61B 5/00(2006.01) (86) International application number: PCT/US2014/065774 (87) International publication number: WO 2015/073871 (21.05.2015 Gazette 2015/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 14.11.2013 US 201361904018 P (71) Applicants: The George Washington University Washington, DC 20052 (US) Luxcath, LLC Boston, Massachusetts 02110 (US)	(72) Inventors: MERCADER, Marco A. Arlington, Virginia 22202 (US) SARVAZYAN, Narine Potomac, Maryland 20854 (US) RANSBURY, Terrance J. Chapel Hill, North Carolina 27517 (US) ARMSTRONG, Kenneth C. Cary, North Carolina 27513 (US) AMIRANA, Omar Cambridge, Massachusetts 02141 (US) (74) Representative: Hollywood, Jane Constance  Olswang LLP 90 High Holborn London WC1V 6XX London WC1V 6XX (GB)