(19)

(11)

EP 3 068 379 A1

(12)

(43) Date of publication: 21.09.2016 Bulletin 2016/38 (21) Application number: 14799989.0 (22) Date of filing: 11.11.2014

(51) International Patent Classification (IPC):  A61K 9/16(2006.01) A61K 31/137(2006.01) A61K 9/20(2006.01) (86) International application number: PCT/EP2014/074246 (87) International publication number: WO 2015/071248 (21.05.2015 Gazette 2015/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 15.11.2013 WO PCT/EP2013/073926 (71) Applicant: Synthon BV 6545 CM Nijmegen (NL)	(72) Inventors: HEUVEL VAN DEN, Denny Johan Marijn NL-6545 CM Nijmegen (NL) SWAANS, Henricus Cornelis Willibrordus NL-6545 CM Nijmegen (NL)