PHARMACEUTICAL COMPOSITION CONTAINING GLUTARIMIDE DERIVATIVES, AND APPLICATION THEREOF FOR TREATING EOSINOPHILIC DISEASES

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(11)

EP 3 069 720 A8

(12)	CORRECTED EUROPEAN PATENT APPLICATION
	published in accordance with Art. 153(4) EPC

(15)	Correction information:
	Corrected version no 1 (W1 A1)

(48)	Corrigendum issued on:
	04.10.2017 Bulletin 2017/40

(43)	Date of publication:
	21.09.2016 Bulletin 2016/38

(21)	Application number: 14861410.0

(22)	Date of filing: 12.11.2014

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International Patent Classification (IPC):

A61K 31/45^(2006.01)
C07D 211/88^(2006.01)
A61P 37/08^(2006.01)
A61P 1/00^(2006.01)

A61K 31/454^(2006.01)
A61K 47/00^(2006.01)
A61P 11/00^(2006.01)

(86)	International application number:
	PCT/RU2014/000855

(87)	International publication number:
	WO 2015/072893 (21.05.2015 Gazette 2015/20)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME

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Priority:

14.11.2013 RU 2013150861

(71)	Applicant: Obschestvo S Ogranichennoi Otvetstvennostiyu "Pharmenterprises"
	Moscow 119571 (RU)

(72)	Inventors:
	NEBOLSIN, Vladimir Evgenievich Moscow 113648 (RU) KROMOVA, Tatyana Alexandrovna Kaluga 248010 (RU) RYDLOVSKAYA, Anastasia Vladimirovna St.Petersburg 198255 (RU) CHUCHALIN, Alexander Grigorievich Moscow 119454 (RU)

(74)	Representative: Hoffmann Eitle
	Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)

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References cited: :

(54)	PHARMACEUTICAL COMPOSITION CONTAINING GLUTARIMIDE DERIVATIVES, AND APPLICATION THEREOF FOR TREATING EOSINOPHILIC DISEASES

(57) The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their use as a therapeutic agent for the treatment of eosinophilic diseases, preferably of allergic nature, in particular bronchial asthma, allergic rhinitis, polypous rhinosinusopathies, eosinophilic colitis, eosinophilic syndrome, allergic conjunctivitis, atopic dermatitis, Churg-Strauss syndrome, anaphylactic shock, Quincke's edema, eosinophilic vasculitis, eosinophylic esophagitis, eosinophilic gastroenteritis, or fibroses. The invention also relates to pharmaceutical compositions comprising glutarimide derivatives of general formula (I):