(19)

(11)

EP 3 073 996 A1

(12)

(43) Date of publication: 05.10.2016 Bulletin 2016/40 (21) Application number: 14802452.4 (22) Date of filing: 25.11.2014

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61K 31/55(2006.01) (86) International application number: PCT/EP2014/075485 (87) International publication number: WO 2015/078845 (04.06.2015 Gazette 2015/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 28.11.2013 EP 13194884 (71) Applicant: Synthon Biopharmaceuticals B.V. 6545 CM Nijmegen (NL)	(72) Inventors: KELTJENS, Rolf NL-6545 CM Nijmegen (NL) EUPEN VAN, Jacobus Theodorus Henricus NL-6545 CM Nijmegen (NL) RIETMAN, Bernard Herman NL-6545 CM Nijmegen (NL) MURPANI, Deepak NL-6545 CM Nijmegen (NL) (74) Representative: Mendivil Gil, Maria Dolores et al Synthon BV IP Research P.O. Box 7071 6503 GN Nijmegen 6503 GN Nijmegen (NL)