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EP 3 074 750 A1

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(43) Date of publication: 05.10.2016 Bulletin 2016/40 (21) Application number: 14815053.5 (22) Date of filing: 25.11.2014

(51) International Patent Classification (IPC):  G01N 15/14(2006.01) G21K 1/00(2006.01) G02B 21/32(2006.01) C12N 5/071(2010.01) G01N 21/65(2006.01) (86) International application number: PCT/IB2014/066319 (87) International publication number: WO 2015/075698 (28.05.2015 Gazette 2015/21)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 25.11.2013 IT RM20130648 (71) Applicant: Consiglio Nazionale Delle Ricerche 00185 Roma (IT)

(72) Inventors: DE LUCA, Anna Chiara I-80131 Napoli (IT) BALDUZZI, Donatella I-24040 Stezzano (BG) (IT) COPPOLA, Giuseppe I-80131 Napoli (IT) GALLI, Andrea I-24035 Curno (BG) (IT) SIRLETO, Luigi I-80131 Napoli (IT) PUGLISI, Roberto I-26828 Turano Lodigiano (LO) (IT) FERRARA, Maria Antonietta I-80131 Napoli (IT) FERRARO, Pietro I-80078 Pozzuoli (NA) (IT) (74) Representative: Di Giovine, Paolo  Società Italiana Brevetti S.p.A. Piazza di Pietra, 38-39 00186 Roma 00186 Roma (IT)