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(11)

EP 3 076 958 A1

(12)

(43) Date of publication: 12.10.2016 Bulletin 2016/41 (21) Application number: 14799726.6 (22) Date of filing: 13.11.2014

(51) International Patent Classification (IPC):  A61K 31/07(2006.01) A61K 31/198(2006.01) A61K 31/355(2006.01) A61K 31/4415(2006.01) A61K 31/592(2006.01) A61K 31/714(2006.01) A61K 33/26(2006.01) A61K 33/34(2006.01) A61K 31/195(2006.01) A61K 31/205(2006.01) A61K 31/375(2006.01) A61K 31/525(2006.01) A61K 31/593(2006.01) A61K 33/04(2006.01) A61K 33/30(2006.01) (86) International application number: PCT/EP2014/074424 (87) International publication number: WO 2015/082180 (11.06.2015 Gazette 2015/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 05.12.2013 EP 13195774 (71) Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. 00144 Rome (IT)	(72) Inventors: VIRMANI, Ashraf I-00040 Ariccia (Roma) (IT) ZERELLI, Safouane NL-3532 HJ Utrech (NL) (74) Representative: Hiebl, Inge Elisabeth  Kraus & Weisert Patentanwälte PartGmbB Thomas-Wimmer-Ring 15 80539 München 80539 München (DE)