(19)

(11)

EP 3 086 637 A1

(12)

(43) Date of publication: 02.11.2016 Bulletin 2016/44 (21) Application number: 15813960.0 (22) Date of filing: 25.11.2015

(51) International Patent Classification (IPC):  A01K 67/027(2006.01) C07K 14/705(2006.01) G01N 33/50(2006.01) (86) International application number: PCT/US2015/062614 (87) International publication number: WO 2016/089692 (09.06.2016 Gazette 2016/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 05.12.2014 US 201462087992 P (71) Applicant: Regeneron Pharmaceuticals, Inc. Tarrytown, NY 10591-6707 (US)	(72) Inventors: GURER, Cagan Tarrytown, NY 10591-6707 (US) IOFFE, Ella Tarrytown, NY 10591-6707 (US) MUJICA, Alexander Tarrytown, NY 10591-6707 (US) THURSTON, Gavin Tarrytown, NY 10591-6707 (US) (74) Representative: Nicholls, James Ronald  J A Kemp 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)