(19)

(11)

EP 3 102 206 A1

(12)

(43) Date of publication: 14.12.2016 Bulletin 2016/50 (21) Application number: 14881460.1 (22) Date of filing: 07.02.2014

(51) International Patent Classification (IPC):  A61K 31/436(2006.01) (86) International application number: PCT/US2014/015387 (87) International publication number: WO 2015/119624 (13.08.2015 Gazette 2015/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (71) Applicant: The Regents of The University of Michigan Ann Arbor, Michigan 48109 (US)	(72) Inventor: SALTIEL, Alan R. San Diego, CA 92127-3801 (US) (74) Representative: Glawe, Delfs, Moll  Partnerschaft mbB von Patent- und Rechtsanwälten Postfach 13 03 91 20103 Hamburg 20103 Hamburg (DE)