(19)
(11) EP 3 107 914 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
17.07.2019 Bulletin 2019/29

(45) Mention of the grant of the patent:
30.01.2019 Bulletin 2019/05

(21) Application number: 15706282.9

(22) Date of filing: 20.02.2015
(51) International Patent Classification (IPC): 
C07D 487/04(2006.01)
A61P 35/00(2006.01)
 A61K 31/519(2006.01)
(86) International application number:
PCT/GB2015/050494
(87) International publication number:
WO 2015/124941 (27.08.2015 Gazette 2015/34)

(54)

PYRAZOLO[1,5-A]PYRIMIDINE-5,7-DIAMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE

PYRAZOL[1,5-A]PYRIMIDIN-5,7-DIAMIN-VERBINDUNGEN ALS CDK-INHIBITOREN UND DEREN THERAPEUTISCHE VERWENDUNG

PYRAZOLO[1,5-A]PYRIMIDINE-5,7-DIAMINES EN TANT QU'INHIBITEURS DE CDK ET LEUR UTILISATION THÉRAPEUTIQUE

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30) Priority: 21.02.2014 GB 201403093

(43) Date of publication of application:
28.12.2016 Bulletin 2016/52

(73) Proprietors:
  • CANCER RESEARCH TECHNOLOGY LIMITED
    London, Greater London EC1V 4AD (GB)
  • IP2IPO Innovations Limited
    London EC4N 8AF (GB)
  • Emory University
    Atlanta, GA 30322 (US)

(72) Inventors:
  • BONDKE, Alexander
    14548 Caputh (DE)
  • KROLL, Sebastian
    London Greater London SW7 2AZ (GB)
  • BARRETT, Anthony
    London Greater London SW7 2AZ (GB)
  • FUCHTER, Matthew
    London Greater London SW7 2AZ (GB)
  • SLAFER, Brian
    Lemont, IL 60439 (US)
  • ALI, Simak
    London Greater London W12 0NN (GB)
  • COOMBES, Charles
    London Greater London W12 0NN (GB)
  • SNYDER, James Patrick
    Atlanta, GA 30329 (US)

(74) Representative: Mewburn Ellis LLP 
City Tower 40 Basinghall Street
London EC2V 5DE
London EC2V 5DE (GB)


(56) References cited: : 
WO-A1-2004/087707
WO-A1-2011/068667
 WO-A1-2008/151304
   
       
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).